Neuroradiology

Virchow robin perivascular space

(Rudolf Ludwig Karl Virchow, 1821-1902, German writer, editor, politician, statesman, ethnologist, archaeologist and pathologist, and Philippe Robin, 1821-1885, French anatomist), a CSF-filled space that surrounds the small arterial vessels that penetrate the cerebral cortex and surface. They are more numerous in the white matter of the centrum semiovale and in the region of the anterior perforated substance. Sometimes they may be very numerous and very large, particularly in the region of the lower basal ganglia. Since they are CSF-filled spaces their CT appearance is that of hypodense fluid-filled spaces; at MRI (Fig.1) they are hypointense as CSF in T1-weighted and FLAIR images, isointense in proton density and hyperintense in T2-weighted images.

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Fig.1

a. MR, T2-weighted axial image. Dilated perivascular space around a lenticulostriate artery (arrowhead) b, c. MR, axial T2 (b) and proton density (c) weighted images in the same patient. Small bilateral hyperintense punctate areas in the subcortical white matter represent dilated perivascular space of perforating cortical medullary arterioles. They are not seen on proton density images.
Virchow robin perivascular space, Fig.1 (a)
Virchow robin perivascular space, Fig.1 (b)
Virchow robin perivascular space, Fig.1 (c)