Neuroradiology

Leukokoria

(from Greek "white pupil"), the white appearance assumed by the pupil when a lesion of the posterior wall of the globe or of the vitreous humour causes a reflection of the light. In the child leukokoria is often the only sign of important lesions of the globe such as retinoblastoma. An overview of the most important causes of leukokoria is given in Table 1.

Leukokoria, Table 1. Most common causes of leukokoria.

Developmental
Coat's disease
Persistent hyperplastic primary vitreous humour
Retinal dysplasia
Congenital retinal fold
Coloboma
Tumour
Retinoblastoma
Medulloepithelioma
Inflammatory
Sclerosing endophthalmitis
Degenerative
Cataract
Retrolental fibroplasia
Trauma
Organized vitreous haemorrhage
Long-standing retinal detachment

FS