Neuroradiology

Fibromuscular dysplasia

condition of unknown aetiology that involves the extracranial internal carotid arteries and vertebral arteries. The internal carotid is involved in about 75% of cases and the vertebral in less than 25%. It is characterized by narrowing of the affected vessel with a string of beads appearance (Fig.1), due to focal annular repetitive intimal and medial proliferative changes. Not infrequently an incidental finding, fibromuscular hyperplasia may be a cause of dissection and is associated with an increased incidence of intracranial aneurysms.

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Fig.1

String of beads appearance of the left internal carotid artery in a patient with fibromuscular dysplasia and intracranial aneurysm.
Fibromuscular dysplasia, Fig.1