Neuroradiology

Bright spot

an early impressionistic definition of the T1 MR appearance of the posterior pituitary. When MR was first used, the T1 hyperintensity of the posterior pituitary (Fig.1) struck the viewer's imagination and was first attributed to fat and subsequently to neurophysin carrying vasopressin and oxytocin. The "bright spot" is present in almost all normal subjects and absent in all patients with diabetes insipidus.

GS

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Fig.1

a. MR, T1-weighted midline sagittal image. The marked hyperintensity of the posterior pituitary within the sella turcica is well seen. b. MR, T1-weighted axial image. The position of the posterior pituitary hyperintensity against the dorsum sella, between the two posterior clinoids, within the sella turcica, may be appreciated also in the axial plane.
Bright spot, Fig.1 (a)
Bright spot, Fig.1 (b)