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Chest Imaging

Adenocarcinoma, pulmonary

the most common cell type of lung cancer accounting for approximately 50% of all cases. It is particularly frequent in women and nonsmokers. Tumours are characteristically peripheral in location and consequently most often asymptomatic and incidentally discovered on chest radiography. Pathologically, adenocarcinomas are composed of papillary structures and formation of glands, and contain intracellular or extracellular mucin. Their growth is typically expansile from the periphery of the lung but occasionally the neoplasm occurs more centrally involving the bronchi. Radiologically, adenocarcinomas present as a solitary pulmonary nodule or mass, most often with ill-defined and spiculated contours and lobulations (Fig.1). They typically grow slowly but tend to metastasize early (see lung cancer staging).

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Fig.1

CT scan in a patient with primary adenocarcinoma of the lung incidentally discovered on a CT examination. The neoplasm is seen as a small, ill-defined nodule of relatively low density (arrow).
Adenocarcinoma, pulmonary, Fig.1