Stress fracture of the neural arch of the vertebra, or spondylolysis, frequently occurs in conjunction with spina bifida. There may be a genetic influence in some cases.
An increased frequency of spina bifida is seen in patients with myositis ossificans progressiva, Klippel Feil syndrome and defects of the pars interarticularis.
Coxa vara deformity has been reported in children with spina bifida and may be accompanied by spontaneous separation of the metaphysis and epiphysis of the femur.
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