Raynaud's phenomenon

(Maurice Raynaud, 1834 - 1881, French physician), intermittent or paroxysmal pallor or ischaemia of the fingers and toes from ischaemia, occurring after exposure to cold temperatures or as a result of stress. The idiopathic or primary condition is known as Raynaud's disease. Raynaud's phenomenon is relieved by heat. Among the manifestations of this condition are cyanosis, pain, burning, numbness, swelling and hyperhidrosis. Diseases associated with Raynaud's phenomenon include scleroderma, collagen vascular disorders, obstructive arterial disorders, drug intoxications, neurological and neoplastic processes, and thermal or occupational trauma.

Raynaud's phenomenon is also one of the features of acrosclerosis, CRST syndrome, and CREST syndrome. In addition, it is an uncommon manifestation in acromegaly.