Musculoskeletal ImagingProgeria
a
congenital disorder characterized by striking premature senility, with many children dying of coronary
artery disease before the age of 10 years. Among the manifestations of this disease are
dwarfism, brown pigmentation of the trunk, loss of subcutaneous fat, receding chin, and exophthalmos. On radiographs hypoplasia of facial bones and mandible,
acro osteolysis of terminal phalanges and of the
clavicle, delayed closure of cranial sutures and
coxa valga may be evident (
Fig.1).
DR/RB
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a. AP radiograph of the chest demonstrates hypoplasia of the clavicles.
b. AP radiograph of the pelvis demonstrates bilateral hip dysplasia and coxa valga.
(Courtesy of Brian Howard, MD, Charlotte, NC)
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Progeria, Fig.1 (a) | | Progeria, Fig.1 (b) | |