Musculoskeletal ImagingPoems syndrome
a combination of plasma cell dyscrasia, chronic progressive polyneuropathy, and endocrine abnormalities such as diabetes mellitus. This syndrome is of unknown cause and takes its name from the typical features: polyneuropathy, organomegaly, endocrinopathy, M proteins and skin changes. Numerous other characteristics can be noted. However, patients do not have an increased prevalence of amyloidosis and rarely reveal Bence Jones proteinuria. Bone proliferation occurs at entheses (sites of tendon and ligament attachment to bone). Particularly characteristic are irregular bony excrescences on the posterior elements of the spine and about the sacroiliac and costovertebral joints (Fig.1).
DR/RB
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AP radiograph of the pelvis in a patient with POEMS syndrome demonstrates numerous sclerotic foci in the pelvis and femora owing to plasma cell myeloma.
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Poems syndrome, Fig.1 | |