Musculoskeletal ImagingHypopituitarism
decrease or ablation of
pituitary function from various causes, including surgery, infections, irradiation, postpartum necrosis and chromophobe
adenoma. In some cases hypopituitarism is inherited. When the
pituitary is affected during the time of skeletal growth, abnormalities of bone development occur. Delay in the appearance and growth of ossification centres as well as in their fusion and disappearance is characteristic. The growth plate remains open and its metaphyseal side is "closed off" as bone abuts on the cartilaginous tissue. Immature body proportions and facial features, abnormal distribution of fat, and delay in eruption of secondary teeth are among the features of hypopituitarism.
DR