Sarcoidosis, case 1
Clinical history
This 58-year-old female first underwent surgery in 1988 for cervical spinal stenosis. A C2-C6 laminectomy was performed for spinal cord decompression. The dura was not opened at that time. The patient's clinical condition transiently improved, but six months after surgery the symptoms worsened, with progressive gait impairment and loss of strength in both hands.
Neurological examination revealed paresthesias of the left arm, bilateral loss of pain and temperature sensation at the level of C5-T1, and posterior cord type pain. McCormick grade II of disability and minor urinary disturbances were present.
Plain X-ray of the chest was normal and no systemic signs of sarcoidosis were present.
MRI
Image 1: Sagittal T1WI. The cervical spinal cord is enlarged at C2-C6, with inhomogeneous, slightly hypointense signal.
Images 2 - 3: Sagittal Gd T1WI show a focal patchy area of intense contrast enhancement within the spinal cord at the level of T3-T4.
Image 4: Axial T1WI confirms cord edema.
Image 5: Axial Gd T1WI demonstrates the precise location of the intramedullary zones of enhancement.
Surgery
Video 1.
During surgical re-exploration, an infiltrating mass lesion was found and biopsy revealed sarcoidosis.
Stage 1: General view - enlargement of the spinal cord
Stage 2: Opening of the spinal cord in the midline.
Stage 3: Separation of the posterior columns.
Stage 4: An infiltrating process is identified.
Stage 5: A cleavage plane cannot be found
Stage 6: Biopsy.
Stage 7: Debulking with CUSA (Cavitron Ultrasonic Surgical Aspirator).
Post-operative clinical course
The patient's neurological condition worsened immediately after surgery. The patient improved rapidly after corticosteroids were administered.
Post operative MRI (immediately after surgery)
Images 6 and 8: Sagittal and axial T1WI. Persistent enlargement of the spinal cord, heterogeneously decreased signal characteristics.
Images 7 and 9: Sagittal and axial Gd T1WI. Contrast enhancement is still identified at the C3-C4 level.
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- Sarcoidosis
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Sarcoidosis, case 1, Fig. 1 | | Sarcoidosis, case 1, Fig. 2 | | Sarcoidosis, case 1, Fig. 3 |
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Sarcoidosis, case 1, Fig. 4 | | Sarcoidosis, case 1, Fig. 5 | | Sarcoidosis, case 1, Fig. 6 |
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Sarcoidosis, case 1, Fig. 7 | | Sarcoidosis, case 1, Fig. 8 | | Sarcoidosis, case 1, Fig. 9 |